The Science Behind PRP and PRF: Harnessing the Body’s Healing PowerThe Science Behind PRP and PRF: Harnessing the Body’s Healing Power

In today’s esthetic landscape, patients are increasingly drawn to natural, regenerative treatments—options that stimulate the body’s own healing processes without synthetic chemicals or surgery. That’s where Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) come in. These powerful, patient-derived therapies are transforming the way providers approach skin rejuvenation and hair restoration. At the Esthetic Skin Institute (ESI) in Ft. Lauderdale, and at training locations nationwide, we offer comprehensive, hands-on courses in both PRP and PRF to help providers elevate their practice with cutting-edge science.


What is PRP?

PRP is a concentration of platelets extracted from a patient’s own blood. These platelets are rich in growth factors that promote cellular regeneration, collagen production, and tissue repair. The process involves:


  • Drawing a small amount of the patient’s blood

  • Spinning it in a centrifuge to isolate the platelet-rich layer

  • Injecting or microneedling the PRP into targeted areas

PRP is commonly used to treat:


  • Fine lines and wrinkles

  • Acne scars and texture issues

  • Hair thinning and alopecia

  • Under-eye rejuvenation

At ESI, students gain real-world experience performing PRP treatments under the guidance of expert instructors.


What is PRF?

PRF is the next generation of platelet therapy. Like PRP, it is derived from the patient’s blood—but with a lower spin speed and no anticoagulants, PRF preserves more white blood cells, fibrin, and stem cells. This leads to:


  • Slower, more sustained release of growth factors

  • Improved wound healing

  • Longer-lasting results

PRF can be used in all the same areas as PRP, and it’s especially popular for undereye rejuvenation, hair restoration, and combination treatments with microneedling or fillers.


PRP vs. PRF: What’s the Difference?

Feature PRP PRF
Anticoagulants Yes No
Centrifuge Speed High Low
Growth Factor Release Fast (Short-Lived) Slow (long-lasting)
Stem Cells & Fibrin Minimal Higher concentration
Clinical Impact Excellent for skin, hair More regenerative and volumizing

Both treatments offer incredible results when applied with precision and expertise. That’s why ESI emphasizes hands-on training with live models, ensuring you master both the science and technique.


Why Train with ESI?

Whether you’re based in Ft. Lauderdale or traveling from another state, ESI provides top-tier education in regenerative aesthetics. Our courses are:



  • Led by industry experts

  • Backed by 25+ years of experience

  • Designed for nurses, NPs, PAs, and MDs

  • Focused on real-world application and safety

  • You’ll learn everything from blood draw techniques and sterile prep to advanced application methods and post-treatment care.


Bring Regenerative Aesthetics to Your Practice

PRP and PRF are more than trends—they’re part of the future of aesthetic medicine. With Esthetic Skin Institute, you’ll gain the knowledge and confidence to offer these transformative treatments safely and effectively.


🔬 View Upcoming PRP/PRF Training Dates at ESIW.com